When Discontinuing SSRI Antidepressants Is a Challenge: Management Tips

Am J Psychiatry. 2018 Dec 1;175(12):1176-1184. doi: 10.1176/appi.ajp.2018.18060692.

Authors

Manish K Jha¹, A John Rush¹, Madhukar H Trivedi¹

Affiliation

¹ From the Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas; Duke-National University of Singapore, Singapore; the Department of Psychiatry, Duke University Medical School, Durham, N.C.; and Texas Tech Health Sciences Center-Permian Basin, Midland-Odessa.

PMID: 30501420
DOI: 10.1176/appi.ajp.2018.18060692

No abstract available

Keywords: Antidepressants; Discontinuation; Drug Side Effects-Other; Selective Serotonin Reuptake Inhibitors.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Antidepressive Agents, Second-Generation / administration & dosage
Antidepressive Agents, Second-Generation / therapeutic use*
Depressive Disorder, Major / drug therapy
Diagnosis, Differential
Female
Humans
Paroxetine / administration & dosage
Paroxetine / therapeutic use*
Risk Factors
Selective Serotonin Reuptake Inhibitors / administration & dosage
Selective Serotonin Reuptake Inhibitors / therapeutic use*
Substance Withdrawal Syndrome / diagnosis
Substance Withdrawal Syndrome / etiology

Substances

Antidepressive Agents, Second-Generation
Serotonin Uptake Inhibitors
Paroxetine