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Uterus transplantation for absolute uterine factor infertility: Surgery, immunosuppression, and obstetric management

Mats Brännström, MD, PhD
César Díaz-García, MD
Section Editor
Tommaso Falcone, MD, FRCSC, FACOG
Deputy Editor
Kristen Eckler, MD, FACOG


Uterus transplantation is a highly experimental procedure for the treatment of absolute uterine factor infertility (AUFI). AUFI refers to infertility that is completely attributable to uterine absence (congenital or surgical) or an abnormality (anatomic or functional) that prevents embryo implantation or completion of pregnancy to term. This topic will review the surgeries for the donor and recipient, immunosuppression, and obstetric issues involved in uterus transplantation. The intent of this topic is to provide an overview of the critical issues for clinicians and patients; the topic is based on the experience of the authors and should not be used for treatment decisions.

Related discussions on the ethical issues, patient selection, and consent involved in uterus transplantation, as well as topics on solid organ transplantation, are presented separately.

(See "Uterus transplantation for absolute uterine factor infertility: Ethics, patient selection, and consent".)

(See "Overview of care of the adult kidney transplant recipient".)

(See "Transplantation immunobiology".)

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Literature review current through: Nov 2017. | This topic last updated: Aug 21, 2017.
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