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Uterus transplantation for absolute uterine factor infertility: Ethics, patient selection, and consent

Mats Brännström, MD, PhD
César Díaz-García, MD
Section Editor
Tommaso Falcone, MD, FRCSC, FACOG
Deputy Editor
Kristen Eckler, MD, FACOG


Historically, no restorative treatment has been available for women with absolute uterine factor infertility (ie, uterus absence or non-function). For these women, alternative pathways to parenthood have included adoption or foster parenting and, in countries where available, use of a gestational carrier. However, gestational surrogacy has limited availability worldwide and, for some women, the desire to carry and birth a child make the option of uterus transplantation appealing. This topic will discuss the ethics, indications, and patient selection for uterus transplantation, an experimental approach to restoring fertility in women with absolute uterine factor infertility. The purpose of this topic is to provide information on this developing technology for clinicians and patients; the topic is not intended to be used for treatment decisions.

Specific discussion of the procedures for uterus transplantation and general issues related to organ transplantation can be found in the following topics:

(See "Uterus transplantation for absolute uterine factor infertility: Surgery, immunosuppression, and obstetric management".)

(See "Transplantation immunobiology".)

(See "Overview of immunosuppressive agents used for prevention and treatment of graft-versus-host disease".)

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Literature review current through: Nov 2017. | This topic last updated: Dec 04, 2017.
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