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Urogenital tuberculosis

R Kasi Visweswaran, MD, DM, FRCP (Edin)
Vernon M Pais, Jr, MD
Jodie Dionne-Odom, MD
Section Editors
C Fordham von Reyn, MD
Gary C Curhan, MD, ScD
Deputy Editors
Elinor L Baron, MD, DTMH
Alice M Sheridan, MD


Urogenital tuberculosis (TB) is the second most common form of extrapulmonary tuberculosis after lymph node involvement [1]. Urogenital TB occurs in 2 to 20 percent of individuals with pulmonary tuberculosis [1-3]. Among patients with miliary disease, hematogenous seeding of the urogenital tract occurs in 25 to 62 percent of cases [1]. In one review including more than 9000 patients with TB, urogenital TB affected two males to each female, with a mean age of 40 years (range 5 to 90 years) [4].

Issues related to urogenital TB are reviewed here; issues related to pulmonary and other forms of TB are discussed separately. (See related topics.)

Rarely, tuberculous bacilli may enter the urinary tract via intravesical instillation of the attenuated live Bacillus Calmette-Guérin (BCG) to treat bladder cancer; this is discussed separately. (See "Infectious complications of intravesical BCG immunotherapy".)


Issues related to pathogenesis of urogenital tuberculosis (TB) are discussed here; general issues related to pathogenesis of TB are discussed separately. (See "Natural history, microbiology, and pathogenesis of tuberculosis".)

Renal and urologic tuberculosis — Tuberculosis involving the kidney and urologic system has two forms. The classical presentation occurs most commonly; it primarily involves the urinary collecting system (including renal pelvis, calyces, ureters, and bladder). Less commonly, renal parenchymal lesions occur, including interstitial nephritis and glomerulonephritis [5].

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Literature review current through: Nov 2017. | This topic last updated: Aug 02, 2017.
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