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Treatment and prognosis of cutaneous mastocytosis

Mariana C Castells, MD, PhD
Cem Akin, MD, PhD
Section Editor
Sarbjit Saini, MD
Deputy Editor
Anna M Feldweg, MD


Cutaneous mastocytosis describes a group of disorders characterized by the presence of excessive numbers of mast cells in the skin. Patients with cutaneous mastocytosis do not fulfill diagnostic criteria for systemic mastocytosis and show no evidence of organ involvement other than the skin.

Forms of cutaneous mastocytosis include three variants recognized by the World Health Organization (WHO) [1]:

Maculopapular cutaneous mastocytosis (MPCM) or urticaria pigmentosa (UP) with two variants – Monomorphic and polymorphic [2]

Diffuse cutaneous mastocytosis

Solitary cutaneous mastocytoma

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Literature review current through: Nov 2017. | This topic last updated: Jul 24, 2017.
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