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Transfusion-associated circulatory overload (TACO)

Arthur J Silvergleid, MD
Section Editor
Steven Kleinman, MD
Deputy Editor
Jennifer S Tirnauer, MD


Reactions to blood component transfusion can range from mild to potentially fatal. Transfusion-associated circulatory overload (TACO) is a common transfusion reaction in which pulmonary edema develops primarily due to volume excess or circulatory overload. TACO typically occurs in patients who receive a large volume of a transfused product over a short period of time, or in those with underlying cardiovascular or renal disease.

This topic reviews the clinical manifestations, diagnosis, management, and prevention of TACO.

A general approach to a suspected transfusion reaction, as well as other specific reactions, are presented in detail separately:

General approach – (See "Approach to the patient with a suspected acute transfusion reaction".)

Transfusion-related acute lung injury (TRALI) – (See "Transfusion-related acute lung injury (TRALI)".)

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Literature review current through: Dec 2017. | This topic last updated: Jan 11, 2017.
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