Transfusion-associated circulatory overload (TACO)
- Arthur J Silvergleid, MD
Arthur J Silvergleid, MD
- Section Editor — Transfusion Medicine
- Affiliate Associate Professor, Department of Pathology and Cell Biology
- University of South Florida, College of Medicine
- Medical Director, OneBlood, Inc.
Reactions to blood component transfusion can range from mild to potentially fatal. Transfusion-associated circulatory overload (TACO) is a common transfusion reaction in which pulmonary edema develops primarily due to volume excess or circulatory overload. TACO typically occurs in patients who receive a large volume of a transfused product over a short period of time, or in those with underlying cardiovascular or renal disease.
This topic reviews the clinical manifestations, diagnosis, management, and prevention of TACO.
A general approach to a suspected transfusion reaction, as well as other specific reactions, are presented in detail separately:
●General approach – (See "Approach to the patient with a suspected acute transfusion reaction".)
●Transfusion-related acute lung injury (TRALI) – (See "Transfusion-related acute lung injury (TRALI)".)To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- PATHOPHYSIOLOGY AND RISK FACTORS
- CLINICAL PRESENTATION
- DIAGNOSTIC TESTING
- Evaluation and diagnosis
- DIFFERENTIAL DIAGNOSIS
- Transfusion reactions/TRALI
- Other causes of heart failure
- Pulmonary embolism
- Overview of prevention
- Transfusion rates
- Reducing RBC volume
- SUMMARY AND RECOMMENDATIONS