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Medline ® Abstract for Reference 20

of 'Systemic chemotherapy for cancer in elderly persons'

20
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Role of red blood cells in pharmacokinetics of chemotherapeutic agents.
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Schrijvers D, Highley M, De Bruyn E, Van Oosterom AT, Vermorken JB
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Anticancer Drugs. 1999;10(2):147.
 
After oral or parenteral administration of chemotherapeutic agents, these drugs are transported to the tissues by the blood in different fractions: plasma water, plasma proteins or cells. In this review, the role of the red blood cell in storage, transport and metabolism of different anti-cancer drugs is described.
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Department of Medical Oncology, University Hospital Antwerp, Edegem, Belgium. Dirk.Schrijvers@uza.uia.ac.be
PMID