Medline ® Abstract for Reference 20
of 'Systemic chemotherapy for cancer in elderly persons'
Role of red blood cells in pharmacokinetics of chemotherapeutic agents.
Schrijvers D, Highley M, De Bruyn E, Van Oosterom AT, Vermorken JB
Anticancer Drugs. 1999;10(2):147.
After oral or parenteral administration of chemotherapeutic agents, these drugs are transported to the tissues by the blood in different fractions: plasma water, plasma proteins or cells. In this review, the role of the red blood cell in storage, transport and metabolism of different anti-cancer drugs is described.
Department of Medical Oncology, University Hospital Antwerp, Edegem, Belgium. Dirk.Schrijvers@uza.uia.ac.be