Medline ® Abstract for Reference 19
of 'Systemic chemotherapy for cancer in elderly persons'
Pharmacology of cancer chemotherapy in the older person.
Baker SD, Grochow LB
Clin Geriatr Med. 1997;13(1):169.
With more widespread use of effective chemotherapy, more elderly patients are candidates for treatment with cytotoxic drugs. This article reviews and discusses the relevant age-related factors that may alter drug disposition and its relationship to pharmacokinetics effects and to pharmacodynamic effects in the elderly.
Department of Pharmacology and Medicine, University of Texas Health Science Center, San Antonio, Texas, USA.