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Medline ® Abstract for Reference 16

of 'Surgical management of stress urinary incontinence in women: Bladder neck fascial sling procedures'

Long-term follow-up of porcine dermis pubovaginal slings.
Broussard AP, Reddy TG, Frilot CF 2nd, Kubricht WS 3rd, Gomelsky A
Int Urogynecol J. 2013;24(4):583.
INTRODUCTION AND HYPOTHESIS: Outcomes of xenografts in incontinence surgery are uncommon. Our objective was to report long-term outcomes of women after porcine dermis (PD) bladder neck sling.
METHODS: Seventy women completed a mean follow-up of 62.1 months. "Global cure" equaled SEAPI subjective composite = 0 and visual analog score≥8. "Stress urinary incontinence (SUI) cure" equaled SEAPI-subjective (S) subset = 0 and negative cough stress test.
RESULTS: The SUI cure rate was 42.9 % and global cure rate was 11.4 %. Perioperative complications were seen in<10 % of women. The mean time to SUI recurrence was 10.4 months, with 30 of 40 women redeveloping SUI<12 months after sling. Twenty women (28.6 %) have since undergone additional anti-incontinence procedures. There was a significant postoperative improvement in SEAPI scores, daily pad use, and quality of life (QOL) indices.
CONCLUSIONS: At long-term follow-up, PD is not a durable material in sling surgery. Although QOL generally improves after surgery, most SUI recurrences occurred soon after surgery.