Commonly used immunosuppressive drugs for kidney diseases and pregnancy: focus on open questions

Expert Rev Clin Pharmacol. 2021 Nov;14(11):1321-1323. doi: 10.1080/17512433.2021.1968831. Epub 2021 Aug 19.

Abstract

Pregnancy is still a challenge in women with autoimmune diseases or kidney transplantation. In this context, management of the immunosuppressive therapy is critical, but, in spite of more than 60 years of experience, many issues remain open, also because of the difficulty in disentangling, in complex patients, the effect of the disease and of the frequent multiple treatments. For this purpose, we have tried to synthesize the existing knowledge and the unresolved issues, to support counseling and promote patient empowerment.

Keywords: immunologic diseases; immunosuppressive drugs; kidney diseases; kidney transplants; pregnancy.

Publication types

  • Editorial

MeSH terms

  • Autoimmune Diseases / drug therapy
  • Autoimmune Diseases / immunology
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Immunosuppressive Agents / immunology
  • Kidney Diseases / drug therapy
  • Kidney Diseases / immunology
  • Kidney Transplantation / methods
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / immunology

Substances

  • Immunosuppressive Agents