Prevention of type 2 diabetes mellitus
- David K McCulloch, MD
David K McCulloch, MD
- Washington Permanente Medical Group
- R Paul Robertson, MD
R Paul Robertson, MD
- Pacific Northwest Research Diabetes Institute
- Professor of Medicine and Pharmacology
- University of Washington
- University of Minnesota
Type 2 diabetes mellitus is characterized by hyperglycemia, insulin resistance, and relative impairment in insulin secretion. Although the lifetime risk of type 2 diabetes is high, our ability to predict and prevent type 2 diabetes in the general population is limited. However, individuals at high risk, including those with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), obesity, close relatives with type 2 diabetes, or who are members of certain ethnic groups (Asian, Hispanic, African American), are appropriate candidates for preventive interventions .
The prevention of type 2 diabetes mellitus will be reviewed here. The prevalence, risk factors, and screening for type 2 diabetes are discussed elsewhere. (See "Risk factors for type 2 diabetes mellitus" and "Screening for type 2 diabetes mellitus".)
GOALS OF DIABETES PREVENTION
The goals of diabetes prevention include:
●Delaying the onset of diabetes
●Preserving beta cell functionTo continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
Subscribers log in hereLiterature review current through: Nov 2017. | This topic last updated: Jun 19, 2017.References
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- GOALS OF DIABETES PREVENTION
- OUR APPROACH
- Identify individuals for preventive measures
- Lifestyle modification
- Assess response to lifestyle intervention
- LIFESTYLE INTERVENTION
- - Finnish Diabetes Prevention Study
- - Diabetes Prevention Program
- PHARMACOLOGIC THERAPY
- Choice of drug therapy
- - Metformin
- Drugs not recommended for prevention
- BARIATRIC SURGERY
- SOCIETY GUIDELINE LINKS
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS