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Medline ® Abstract for Reference 45

of 'Post-ERCP perforation'

Endoscopic duodenal perforation: surgical strategies in a regional centre.
Turner RC, Steffen CM, Boyd P
World J Emerg Surg. 2014;9(1):11. Epub 2014 1 24.
BACKGROUND: Duodenal perforation is an uncommon complication of endoscopic retrograde cholangio-pancreatography (ERCP) and a rare complication of upper gastrointestinal endoscopy. Most are minor perforations that settle with conservative management. A few perforations however result in life-threatening retroperitoneal necrosis and require surgical intervention. There is a relative paucity of references specifically describing the surgical interventions required for this eventuality.
METHODS: Five cases of iatrogenic duodenal perforation were ascertained between 2002 and 2007 at Cairns Base Hospital. Clinical features were analyzed and compared, with reference to a review of ERCP at that institution for the years 2005/2006.
RESULTS: One patient recovered with conservative management. Of the other four, one died after initial laparotomy. The other three survived, undergoing multiple procedures and long inpatient stays.
CONCLUSIONS: Iatrogenic duodenal perforation with retroperitoneal necrosis is an uncommon complication of endoscopy, but when it does occur it is potentially life-threatening. Early recognition may lead to a better outcome through earlier intervention, although a protracted course with multiple procedures should be anticipated. A number of surgical techniques may need to be employed according to the individual circumstances of the case.
Department of Surgery, Hobart Clinical School, University of Tasmania, Hobart, Australia. richard.turner@utas.edu.au.