Medline ® Abstract for Reference 28
of 'Pathogenesis of Sjögren's syndrome'
Human herpesvirus-6 (HHV-6, HBLV) in sarcoidosis and lymphoproliferative disorders.
Biberfeld P, Petrén AL, Eklund A, Lindemalm C, Barkhem T, Ekman M, Ablashi D, Salahuddin Z
J Virol Methods. 1988;21(1-4):49.
Serologic studies were done to estimate the antibody prevalence against human herpesvirus 6 (HHV-6) in patients with malignant lymphomas, Sjögren's syndrome and sarcoidosis. Serologic studies showed IgG antibody titers against HHV-6 in up to 41% of patients with sarcoidosis, 50-70% with malignant lymphomas and in 36% with Sjögren's syndrome. In situ hybridization on lymph node biopsies was positive for HHV-6 genome in 1 out of 5 sarcoidosis lymph nodes.
Department of Pathology, Karolinska Institute, Stockholm, Sweden.