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Pathogenesis of inflammatory myopathies

Steven A Greenberg, MD
Section Editors
Ira N Targoff, MD
Jeremy M Shefner, MD, PhD
Deputy Editor
Monica Ramirez Curtis, MD, MPH


The inflammatory myopathies are a group of disorders sharing the common feature of immune-mediated muscle injury. Clinical and histopathological distinctions between these conditions suggest that different pathogenic processes underlie each of the inflammatory myopathies. The most common of these disorders include:

Dermatomyositis (DM)

Overlap syndromes (with another systemic rheumatic disease)

Inclusion body myositis (IBM)

Polymyositis (PM)

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Literature review current through: Nov 2017. | This topic last updated: May 31, 2016.
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