Abstract
This is an image and brief case report of a 13-year-old boy who presented with severe rash and systemic symptoms after starting oxcarbazepine. The patient was diagnosed and treated for Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), a syndrome of fever, rash, and internal organ involvement secondary to medication administration. The image illustrates the rash seen with this drug reaction. The report is followed by a brief review of anticonvulsant hypersensitivity syndrome and DRESS.
MeSH terms
-
Adolescent
-
Anticonvulsants / administration & dosage
-
Anticonvulsants / adverse effects*
-
Anticonvulsants / therapeutic use
-
Carbamazepine / administration & dosage
-
Carbamazepine / adverse effects
-
Carbamazepine / analogs & derivatives*
-
Carbamazepine / therapeutic use
-
Drug Eruptions / blood
-
Drug Eruptions / diagnosis
-
Drug Eruptions / drug therapy
-
Drug Eruptions / etiology*
-
Eosinophilia / blood
-
Eosinophilia / chemically induced*
-
Eosinophilia / drug therapy
-
Fever / chemically induced
-
Fever / diagnosis
-
Fever / drug therapy
-
Glucocorticoids / therapeutic use
-
Humans
-
Male
-
Oxcarbazepine
-
Seizures / drug therapy
-
Treatment Outcome
Substances
-
Anticonvulsants
-
Glucocorticoids
-
Carbamazepine
-
Oxcarbazepine