Medline ® Abstract for Reference 42
of 'Overview of vitamin A'
Liver damage with reversible portal hypertension from vitamin A intoxication: demonstration of Ito cells.
Guarascio P, Portmann B, Visco G, Williams R
J Clin Pathol. 1983;36(7):769.
A patient with sudden onset of ascites and hepatosplenomegaly made a complete recovery after vitamin A was withdrawn. Fluorescence microscopy on embedded tissue provided a simple method of demonstrating the accumulation of fat storage (Ito) cells in the liver.