Overview of endometrial carcinoma
- Steven C Plaxe, MD
Steven C Plaxe, MD
- Professor, Reproductive Medicine
- Director, Gynecologic Oncology
- University of California, San Diego School of Medicine
- Arno J Mundt, MD
Arno J Mundt, MD
- Section Editor — Radiation Therapy
- Chairman of Radiation Oncology
- University of California, San Diego
- Section Editors
- Barbara Goff, MD
Barbara Goff, MD
- Section Editor — Gynecologic Oncology
- Department Chair, Gynecologic Oncology
- University of Washington Medical Center
- Don S Dizon, MD, FACP
Don S Dizon, MD, FACP
- Section Editor – Gynecologic Oncology
- Head of Women's Cancers, Lifespan Cancer Institute
- Director of Medical Oncology, Rhode Island Hospital
- Associate Professor of Medicine, Warren Alpert Medical School of Brown University
- Deputy Editors
- Sadhna R Vora, MD
Sadhna R Vora, MD
- Deputy Editor — Oncology
- Instructor in Medicine
- Harvard Medical School
- Sandy J Falk, MD, FACOG
Sandy J Falk, MD, FACOG
- Director, Editorial Relations — UpToDate
- Deputy Editor — Obstetrics, Gynecology and Women's Health
- Instructor of Obstetrics, Gynecology and Reproductive Biology, Part-time
- Harvard Medical School
Cancer of the endometrium (lining of the uterus) is the most common gynecologic malignancy in developed countries and the second most common in developing countries (cervical cancer is more common). Endometrioid carcinoma is the common site and histologic subtype of endometrial carcinoma and of uterine cancer overall. Endometrioid tumors tend to have a favorable prognosis and typically present at an early stage with abnormal uterine bleeding. Other histologic types of endometrial carcinoma (eg, serous, clear cell) as well as other types of uterine cancer are associated with a poor prognosis.
An overview of endometrial carcinoma will be presented here. Related topics are discussed in detail separately, including:
●Histopathology and pathogenesis (see "Endometrial carcinoma: Histopathology and pathogenesis")
●Epidemiology and risk factors (see "Endometrial carcinoma: Epidemiology and risk factors")
●Clinical features, diagnosis, and screening for high-risk women (see "Endometrial carcinoma: Clinical features and diagnosis")To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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