Medline ® Abstract for Reference 49
of 'Musculoskeletal manifestations of amyloidosis'
Amyloid deposits in surgically removed articular and periarticular tissue.
Ladefoged C, Merrild U, Jørgensen B
In tissue from 13 of 30 patients subjected to meniscectomy, amyloid degeneration was found to varying extent along the surface of the meniscus. Tissue from 30 synovectomies, 30 bursectomies and 30 ganglia showed amyloid deposits in four, six and eight cases, respectively. Amyloid was found significantly more frequently in older patients, but there was no sex difference and no relation to duration of the symptoms or to other histological changes in the tissue. Micro-deposits of amyloid in joint tissue and tissue neighbouring joints are a frequent finding, especially in elderly persons, but the clinical significance of this finding is not clear.
Institute of Pathology, Odense University Hospital, Denmark.