Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs

MeSH terms

• Acute Kidney Injury / chemically induced*
• Adult
• Antimetabolites, Antineoplastic / administration & dosage*
• Antimetabolites, Antineoplastic / adverse effects*
• Antimetabolites, Antineoplastic / blood
• Brain Neoplasms / blood
• Brain Neoplasms / drug therapy
• Drug Interactions
• Gemfibrozil / administration & dosage
• Gemfibrozil / adverse effects
• Hematologic Neoplasms / blood
• Hematologic Neoplasms / drug therapy*
• Humans
• Lymphoma / blood
• Lymphoma / drug therapy
• Male
• Methotrexate / administration & dosage*
• Methotrexate / adverse effects*
• Methotrexate / blood
• Middle Aged
• Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / blood
• Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
• Retrospective Studies
• Risk Factors