Management of moderate to severe knee osteoarthritis
- Leticia Alle Deveza, MD
Leticia Alle Deveza, MD
- Rheumatology Fellow
- Department of Rheumatology, Royal North Shore Hospital
- Institute of Bone and Joint Research, Sydney Medical School
- Kolling Institute of Medical Research, University of Sydney
- Kim Bennell, PhD
Kim Bennell, PhD
- Professor, Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy
- University of Melbourne, Australia
All patients with knee osteoarthritis (OA) should have appropriate interventions that include a combination of nonpharmacologic and pharmacologic treatment modalities. In contrast to patients with mild knee OA, patients with moderate to severe knee OA generally require additional interventions given the degree of functional impairment and impact on quality of life.
The management of moderate to severe knee OA is reviewed here. Separate topic reviews on OA as well as knee pain include the following:
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- OVERALL APPROACH
- Nonpharmacologic measures
- - Exercise
- - Knee braces
- - Walking aids
- - Psychological interventions
- Pharmacologic measures
- - Oral NSAIDs
- Choice and use of oral NSAID
- Efficacy of oral NSAIDs
- Adverse effects of oral NSAIDs
- - Inadequate response to oral NSAIDs or NSAIDs contraindicated
- Intraarticular glucocorticoid injection
- Refractory symptoms
- - Surgery
- THERAPIES LACKING EFFICACY OR OF UNCERTAIN BENEFIT
- SOCIETY GUIDELINE LINKS
- SUMMARY AND RECOMMENDATIONS