Management of early-stage cervical cancer
- J Michael Straughn, Jr, MD
J Michael Straughn, Jr, MD
- Division of Gynecologic Oncology
- University of Alabama at Birmingham
- Catheryn Yashar, MD
Catheryn Yashar, MD
- Associate Professor of Radiation Medicine and Applied Sciences
- University of California San Diego
- Section Editors
- Barbara Goff, MD
Barbara Goff, MD
- Section Editor — Gynecologic Oncology
- Professor of Gynecologic Oncology
- University of Washington
- Arno J Mundt, MD
Arno J Mundt, MD
- Section Editor — Radiation Therapy
- Chairman of Radiation Oncology
- University of California, San Diego
- Don S Dizon, MD, FACP
Don S Dizon, MD, FACP
- Section Editor – Gynecologic Oncology
- Head of Women's Cancers, Lifespan Cancer Institute
- Director of Medical Oncology, Rhode Island Hospital
- Associate Professor of Medicine, Warren Alpert Medical School of Brown University
- Deputy Editors
- Sadhna R Vora, MD
Sadhna R Vora, MD
- Deputy Editor — Oncology
- Instructor in Medicine
- Harvard Medical School
- Sandy J Falk, MD, FACOG
Sandy J Falk, MD, FACOG
- Director, Editorial Relations — UpToDate
- Deputy Editor — Obstetrics, Gynecology and Women's Health
- Instructor of Obstetrics, Gynecology and Reproductive Biology, Part-time
- Harvard Medical School
Women with cervical cancer limited to the uterus have early-stage disease. Treatment options for these women include definitive surgery (modified radical hysterectomy), fertility-sparing surgery, or primary radiation therapy (RT; with or without chemotherapy). The choice of therapy depends on tumor- and patient-defined factors.
The approach to women with early-stage cervical cancers is reviewed here. Treatment of more advanced disease and specific issues regarding the management of cervical adenocarcinomas and small cell cancers are reviewed elsewhere.To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- DEFINITION OF EARLY-STAGE CERVICAL CANCER
- APPROACH TO TREATMENT
- Primary therapy
- - Surgery versus primary RT
- - Surgical treatment
- Radical hysterectomy
- Extrafascial hysterectomy or conization
- Fertility-sparing surgery
- - Primary radiation therapy
- Adjuvant therapy indications
- - Intermediate-risk disease
- Treatment of intermediate-risk disease
- - High-risk disease
- Treatment of high-risk disease
- RT technique
- POSTTREATMENT SURVEILLANCE
- QUALITY-OF-LIFE ISSUES IN CERVICAL CANCER SURVIVORS
- Ovarian failure
- Fertility preservation
- Hormone replacement therapy
- Sexual dysfunction
- SPECIAL CIRCUMSTANCES
- Incidentally diagnosed cancer
- Adenocarcinoma and small cell cancers
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS