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Management of celiac disease in adults

Paul J Ciclitira, MD, PhD, FRCP
Section Editor
J Thomas Lamont, MD
Deputy Editor
Shilpa Grover, MD, MPH, AGAF


Celiac disease can be defined as a condition in which there is an abnormal small intestinal mucosa that improves morphologically when treated with a gluten-free diet and relapses when gluten is reintroduced. The disorder is commonly referred to as "celiac sprue" or "gluten-sensitive enteropathy" in the United States. It was first described by Samuel Gee in 1887, although a similar description of a chronic malabsorptive disorder was recorded as far back as the second century AD [1].

As a general rule, there are six key elements in the management of patients with celiac disease, which can be summarized with the following acronym [2]:

Consultation with a skilled dietitian

Education about the disease

Lifelong adherence to a gluten-free diet

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Literature review current through: Nov 2017. | This topic last updated: Jul 05, 2017.
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