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Medline ® Abstract for Reference 61

of 'Management of acute exacerbations of asthma in adults'

61
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Ketamine by continuous infusion in status asthmaticus.
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Strube PJ, Hallam PL
SO
Anaesthesia. 1986;41(10):1017.
 
A 13-year-old girl was admitted to the intensive care unit with status asthmaticus. Conventional bronchodilator therapy failed to relieve her bronchospasm. In order to try and avoid artificial ventilation, a continuous intravenous infusion of ketamine was used with success. The total dose rate was 40 micrograms/kg minute for a period of 8 hours; this was given at a decreasing rate. She regained consciousness 30 minutes after the end of the infusion and became well orientated after one hour. Ketamine is a useful drug in the intensive treatment of status asthmaticus and should be tried before a decision is taken to start mechanical ventilation.
AD
PMID