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Management and outcome of sepsis in term and late preterm infants

Morven S Edwards, MD
Section Editors
Leonard E Weisman, MD
Sheldon L Kaplan, MD
Deputy Editor
Carrie Armsby, MD, MPH


Sepsis is an important cause of morbidity and mortality among newborn infants. Although the incidence of sepsis in term and late preterm infants is low, the potential for serious adverse outcomes, including death, is of such great consequence that caregivers should have a low threshold for evaluation and treatment for possible sepsis in neonates. The approach discussed below is consistent with guidelines published by the American Academy of Pediatrics (AAP) and the Centers for Disease Control and Prevention (CDC) [1,2].

The treatment and outcome of sepsis in term and late preterm infants will be reviewed here. The epidemiology, clinical features, diagnosis, and evaluation of sepsis in term and late preterm infants, neonatal sepsis in preterm infants, the management of well-appearing infants at risk for group B streptococcal (GBS) infection, and the evaluation of febrile or ill-appearing newborns are discussed separately:

(See "Clinical features, evaluation, and diagnosis of sepsis in term and late preterm infants".)

(See "Clinical features and diagnosis of bacterial sepsis in the preterm infant (<34 weeks gestation)".)

(See "Treatment and prevention of bacterial sepsis in the preterm infant (<34 weeks gestation)".)

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Literature review current through: Nov 2017. | This topic last updated: Jul 31, 2017.
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