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Malignant tracheal tumors

Rogerio C Lilenbaum, MD, FACP
Section Editors
Bruce E Brockstein, MD
Steven E Schild, MD
Eric Vallières, MD, FRCSC
Deputy Editors
Sadhna R Vora, MD
Susanna I Lee, MD, PhD


The epidemiology, pathology, clinical presentation, treatment, and prognosis of malignant primary tracheal tumors will be reviewed here.

Depending upon histology and location, tracheal tumors may overlap with primary lung cancers or head and neck lesions; these are discussed separately.

(See "Overview of the risk factors, pathology, and clinical manifestations of lung cancer".)

(See "Overview of treatment for head and neck cancer".)


Primary tracheal tumors are rare. Population-based studies from tumor registries in Finland, Denmark, Netherlands, and England report annual incidence rates of tracheal cancer of approximately 0.1 per 100,000 per year, with tracheal cancers accounting for less than one-half of 1 percent of all malignant tumors [1-4]. The largest reported series comes from a Surveillance, Epidemiology, and End Results (SEER) analysis of 578 cases of primary tracheal carcinoma identified over a 31-year period [5]. In that series, the median age was 63 years, and 56 percent of patients were male. In other series, the mean age at presentation was approximately 60 to 65 years, and 60 to 70 percent of cases occurred in males [1-4].

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Literature review current through: Nov 2017. | This topic last updated: Sep 28, 2016.
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