Efficacy of propranolol in neuroleptic-induced akathesia

J Clin Psychopharmacol. 1985 Jun;5(3):164-6.

Abstract

The effects of propranolol, 20 to 30 mg/day, on neuroleptic-induced akathesia were compared with those of lorazepam, 2 mg/day, and periods of no treatment. Raters were blind to treatment condition. As reported in prior open studies, propranolol was found to be dramatically effective in reducing akathesia induced by neuroleptic treatment.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Akathisia, Drug-Induced*
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Chronic Disease
  • Female
  • Humans
  • Lorazepam / therapeutic use
  • Male
  • Middle Aged
  • Propranolol / therapeutic use*
  • Psychomotor Agitation / drug therapy
  • Random Allocation
  • Schizophrenia / drug therapy

Substances

  • Antipsychotic Agents
  • Propranolol
  • Lorazepam