Localized lichen myxedematosus
- Franco Rongioletti, MD
Franco Rongioletti, MD
- Professor and Chairman
- Unit of Dermatology
- University of Cagliari, Italy
Lichen myxedematosus (LM, also called papular mucinosis) is a chronic idiopathic cutaneous mucinosis characterized by lichenoid papules, nodules, and/or plaques; mucin deposition and a variable degree of fibrosis in the dermis; and an absence of associated thyroid disease . LM includes three clinicopathologic subsets (table 1) [1,2]:
●Localized LM: A localized papular form of LM with a benign course and lack of systemic involvement.
●Scleromyxedema: A diffuse/generalized papular and sclerodermoid form of LM associated with monoclonal gammopathy and systemic, potentially fatal, manifestations. (See "Scleromyxedema".)
●Atypical or intermediate forms of LM: LM with atypical features or overlapping features of localized LM and scleromyxedema.To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- ASSOCIATED CONDITIONS
- CLINICAL FINDINGS
- Acral persistent papular mucinosis
- Discrete papular lichen myxedematosus
- Cutaneous mucinosis of infancy
- Nodular lichen myxedematosus
- Skin biopsy
- Laboratory tests
- DIFFERENTIAL DIAGNOSIS
- PROGNOSIS AND FOLLOW-UP
- SUMMARY AND RECOMMENDATIONS