Abstract
Three children who developed pulmonary aspergillosis while being treated for leukaemia or non-Hodgkin's lymphoma. Each child continued with intensive myelosuppressive chemotherapy regimens during the infection and each was successfully treated with antifungal prophylaxis based on itraconazole by mouth. Amphotericin B was also given during periods of severe neutropenia. No reactivation of the fungal infection was seen.
MeSH terms
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Amphotericin B / therapeutic use
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Antineoplastic Agents / adverse effects*
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Aspergillosis / diagnostic imaging
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Aspergillosis / prevention & control*
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Child, Preschool
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Drug Therapy, Combination
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Humans
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Itraconazole / therapeutic use
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Lung / diagnostic imaging
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Lung Diseases, Fungal / diagnostic imaging
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Lung Diseases, Fungal / prevention & control*
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Male
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Neutropenia / chemically induced
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Opportunistic Infections / diagnostic imaging
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Opportunistic Infections / prevention & control*
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Radiography
Substances
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Antineoplastic Agents
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Itraconazole
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Amphotericin B