Isoniazid-induced seizures are a rare adverse reaction especially in immunocompetent adults. We report a case of a healthy man with seizures shortly after ingestion of his first therapeutic dose of isoniazid with rifapentine therapy for treatment of latent tuberculosis infection. Only 6 other similar cases are reported in the literature.
Keywords: isoniazid; latent tuberculosis; pyridoxine; seizures; tuberculosis.
© The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.