We report the case of a HIV-positive patient with type 2 diabetes mellitus who presented with uncontrolled blood sugars after the initiation of prophylactic isoniazid (INH) therapy. INH is widely used for prophylaxis and treatment of tuberculosis (TB) around the world and INH-induced hyperglycaemia could be overlooked.
Keywords: Hyperglycaemia; isoniazid; isoniazid prophylaxis therapy.