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Intraarticular and soft tissue injections: What agent(s) to inject and how frequently?

W Neal Roberts, Jr, MD
Section Editor
Daniel E Furst, MD
Deputy Editor
Monica Ramirez Curtis, MD, MPH


This topic will review the following material:

The history of intraarticular injections in the treatment of rheumatic diseases

Considerations in selection of glucocorticoids and the frequency of injections

Investigational approaches to the treatment of rheumatic disorders that involve intraarticular injection

The technique, indications, and complications that can occur with intraarticular and periarticular injections of glucocorticoids, as well as the use of intraarticular hyaluronic acid derivatives, are discussed separately. (See "Joint aspiration or injection in adults: Technique and indications" and "Joint aspiration or injection in adults: Complications" and "Management of knee osteoarthritis", section on 'Hyaluronans' and "Management of moderate to severe knee osteoarthritis", section on 'Intraarticular glucocorticoid injection'.)

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Literature review current through: Sep 2017. | This topic last updated: Apr 18, 2017.
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