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Differential diagnosis of excessive daytime sleepiness
Insufficient sleep
Sleep deprivation
Environmental intrusions
Sleep disorders
Obstructive sleep apnea
Central sleep apnea
Sleep-related hypoventilation or hypoxemia
Central disorders of hypersomnolence 
Narcolepsy type 1 or 2
Kleine-Levin syndrome
Idiopathic hypersomnia
Circadian rhythm sleep-wake disorders
Delayed sleep phase disorder
Advanced sleep phase disorder
Jet lag
Shift work
Restless legs syndrome
Periodic limb movement disorder
Other neurologic disorders
Neurodegenerative disease
Parkinson disease
Dementia with Lewy bodies
Alzheimer disease
Multiple system atrophy
Myotonic dystrophy
Multiple sclerosis
Amyotrophic lateral sclerosis (via sleep-related breathing disorders)
Structural lesions affecting thalamus, hypothalamus, or brainstem
Traumatic brain injury
Encephalitis lethargica
Cerebral trypanosomiasis
Medical and genetic disorders
Hypothyroidism
Obesity
End-stage renal disease
Adrenal insufficiency
Hepatic encephalopathy
Niemann-Pick type C
Prader-Willi syndrome
Psychiatric disorders
Depression
Anxiety
Substance abuse
Alcohol
Narcotics
Prescription opioid abuse
Stimulant withdrawal
Psychogenic sleepiness
Medications
Benzodiazepines
Nonbenzodiazepine sedatives
Antipsychotics
Opioid analgesics
Beta-blockers (lipophilic)
Barbiturates
Antihistamines
Anticonvulsants
Sedative antidepressants
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