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IgA vasculitis (Henoch-Schönlein purpura): Management

Fatma Dedeoglu, MD
Susan Kim, MD, MMSc
Section Editor
Robert Sundel, MD
Deputy Editor
Elizabeth TePas, MD, MS


Immunoglobulin A vasculitis (IgA vasculitis [IgAV]), formerly called Henoch-Schönlein purpura (HSP) [1], is the most common systemic vasculitis of childhood. Ninety percent of cases occur in the pediatric age group. In contrast to other forms of systemic vasculitis, IgAV (HSP) is usually self-limited and is characterized by a tetrad of clinical manifestations that vary in their presence and order of presentation:

Palpable purpura in patients with neither thrombocytopenia nor coagulopathy

Arthralgia and/or arthritis

Abdominal pain

Renal disease

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Literature review current through: Nov 2017. | This topic last updated: Oct 16, 2017.
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