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IgA vasculitis (Henoch-Schönlein purpura): Clinical manifestations and diagnosis

Fatma Dedeoglu, MD
Susan Kim, MD, MMSc
Section Editor
Robert Sundel, MD
Deputy Editor
Elizabeth TePas, MD, MS


Immunoglobulin A vasculitis (IgA vasculitis, IgAV; formerly called Henoch-Schönlein purpura [HSP]) [1], is the most common form of systemic vasculitis in children. Ninety percent of cases occur in the pediatric age group. In contrast to many other forms of systemic vasculitis, IgAV (HSP) is self-limited in the great majority of cases. The disease is characterized by a tetrad of clinical manifestations:

Palpable purpura in patients with neither thrombocytopenia nor coagulopathy


Abdominal pain

Renal disease

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Literature review current through: Sep 2017. | This topic last updated: Oct 13, 2017.
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