Abstract
Renal cortical imaging with 99mTc-dimercaptosuccinic acid (DMSA) has become the imaging test of choice for the diagnosis of acute pyelonephritis. An unusual uptake pattern was observed in a child receiving chemotherapy for a bladder rhabdomyosarcoma. Chemotherapy from ifosfamide produces a specific pattern of injury to the renal tubule that alters uptake of DMSA.
MeSH terms
-
Antineoplastic Agents, Alkylating / administration & dosage
-
Antineoplastic Agents, Alkylating / adverse effects*
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
-
Female
-
Humans
-
Ifosfamide / administration & dosage
-
Ifosfamide / adverse effects*
-
Infant
-
Kidney Diseases / chemically induced*
-
Kidney Diseases / diagnostic imaging*
-
Kidney Tubules / drug effects*
-
Pyelonephritis / diagnostic imaging
-
Radionuclide Imaging
-
Radiopharmaceuticals*
-
Rhabdomyosarcoma, Embryonal / drug therapy
-
Technetium Tc 99m Dimercaptosuccinic Acid*
-
Urinary Bladder Neoplasms / drug therapy
Substances
-
Antineoplastic Agents, Alkylating
-
Radiopharmaceuticals
-
Technetium Tc 99m Dimercaptosuccinic Acid
-
Ifosfamide