Medline ® Abstract for Reference 27
of 'Hyperkalemic periodic paralysis'
Treatment of attacks in hyperkalaemic familial periodic paralysis by inhalation of salbutamol.
Wang P, Clausen T
In fifteen patients with hyperkalaemic familial periodic paralysis, inhalation of salbutamol alleviated hyperkaleamia and paralysis precipitated by exercise or oral administration of potassium chloride. In-vitro studies with rat soleus muscles indicated that the hypokalaemic effect of salbutamol is related to stimulation of the active coupled transport of sodium and potassium in muscle cells. Follow-up studies proved that the inhalation of salbutamol is a simple and adequate method for the treatment of the paralytic episodes in these patients.