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Medline ® Abstract for Reference 27

of 'Hyperkalemic periodic paralysis'

27
TI
Treatment of attacks in hyperkalaemic familial periodic paralysis by inhalation of salbutamol.
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Wang P, Clausen T
SO
Lancet. 1976;1(7953):221.
 
In fifteen patients with hyperkalaemic familial periodic paralysis, inhalation of salbutamol alleviated hyperkaleamia and paralysis precipitated by exercise or oral administration of potassium chloride. In-vitro studies with rat soleus muscles indicated that the hypokalaemic effect of salbutamol is related to stimulation of the active coupled transport of sodium and potassium in muscle cells. Follow-up studies proved that the inhalation of salbutamol is a simple and adequate method for the treatment of the paralytic episodes in these patients.
AD
PMID