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HIV infection in older adults

Nathalie Casau-Schulhof, MD
Section Editor
John G Bartlett, MD
Deputy Editor
Howard Libman, MD, FACP


Most of the literature on human immunodeficiency virus (HIV) infection in older adults defines older as ≥50 years of age. With the increasing survival of HIV-infected patients on antiretroviral therapy (ART) and increased case finding with wider HIV screening, the proportion of HIV-infected patients in this older age bracket has increased substantially [1]. The same recommendations on management of HIV infection in adults and adolescents apply to older adults as well, but certain issues are of particular importance in this population:

Epidemiology, risk factors, and delays in diagnosis due to unsuspected HIV infection

Antiretroviral use in the older population (pharmacokinetics and polypharmacy)

Age-related differences in immune responses to HIV and ART

HIV-related mortality

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Literature review current through: Nov 2017. | This topic last updated: Aug 08, 2017.
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