Persistent oromandibular dystonia and angioedema secondary to haloperidol

BMJ Case Rep. 2017 Oct 4:2017:bcr2017220817. doi: 10.1136/bcr-2017-220817.

Abstract

We report a case in a young man who developed acute, persistent and painful tongue protrusion followed by swelling for more than 24 hours. He had relapse symptoms of schizophrenia and had recently received a single dose of parenteral haloperidol to manage his agitation. His record showed history of similar event and he has been taking atypical antipsychotic for maintenance. Mental state examination on admission revealed an agitated man with disorganised speech, restricted affect, auditory hallucination and persecutory delusion. His dystonia and oedema improved after 3 days. His mental status also recovered with the maintenance of low-potency antipsychotic and anticholinergic antiparkinsonian medications.

Keywords: drugs: psychiatry; psychiatry (drugs and medicines); schizophrenia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angioedema / chemically induced
  • Angioedema / diagnosis*
  • Angioedema / pathology
  • Antipsychotic Agents / adverse effects*
  • Diagnosis, Differential
  • Dystonia / chemically induced
  • Dystonia / diagnosis*
  • Dystonia / pathology
  • Haloperidol / adverse effects*
  • Humans
  • Male
  • Schizophrenia / drug therapy*
  • Tongue Diseases / chemically induced
  • Tongue Diseases / diagnosis*
  • Tongue Diseases / pathology

Substances

  • Antipsychotic Agents
  • Haloperidol