Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction
- Jayanta Roy-Chowdhury, MD, MRCP
Jayanta Roy-Chowdhury, MD, MRCP
- Professor of Medicine and Genetics
- Albert Einstein College of Medicine
- Namita Roy-Chowdhury, PhD
Namita Roy-Chowdhury, PhD
- Professor of Medicine and Genetics
- Albert Einstein College of Medicine
- Xia Wang, MD, PhD
Xia Wang, MD, PhD
- Research Associate
- Albert Einstein College of Medicine
The metabolism of bilirubin by the liver is comprised of four distinct but interrelated stages. (See "Bilirubin metabolism".):
●Uptake from the circulation
●Conjugation with glucuronic acid
●Biliary excretionTo continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- REFERENCE RANGES
- BILIRUBIN OVERPRODUCTION
- GILBERT SYNDROME
- - Impaired bilirubin glucuronidation
- - Increased bilirubin production
- - Genetic defect
- - Histology
- Clinical manifestations
- - Symptoms
- - Physical examination findings
- - Laboratory tests
- - Drug interactions
- - Cholelithiasis
- - Neonatal jaundice
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS