Gilbert syndrome and unconjugated hyperbilirubinemia due to bilirubin overproduction
- Jayanta Roy-Chowdhury, MD, MRCP
Jayanta Roy-Chowdhury, MD, MRCP
- Professor of Medicine and Genetics
- Albert Einstein College of Medicine
- Namita Roy-Chowdhury, PhD
Namita Roy-Chowdhury, PhD
- Professor of Medicine and Genetics
- Albert Einstein College of Medicine
- Xia Wang, MD, PhD
Xia Wang, MD, PhD
- Research Associate
- Albert Einstein College of Medicine
The metabolism of bilirubin by the liver is comprised of four distinct but interrelated stages. (See "Bilirubin metabolism".):
●Uptake from the circulation
●Conjugation with glucuronic acid
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- REFERENCE RANGES
- BILIRUBIN OVERPRODUCTION
- GILBERT SYNDROME
- - Impaired bilirubin glucuronidation
- - Increased bilirubin production
- - Genetic defect
- - Histology
- Clinical manifestations
- - Symptoms
- - Physical examination findings
- - Laboratory tests
- - Drug interactions
- - Cholelithiasis
- - Neonatal jaundice
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS