Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns

Gil Binenbaum; Christie J Bruno; Brian J Forbes; MaryAnn Snyder; Thomas J Mollen; Barbara Schmidt; Iyalla Peterside

doi:10.1016/j.jpeds.2009.11.060

Periocular ulcerative dermatitis associated with gentamicin ointment prophylaxis in newborns

J Pediatr. 2010 Feb;156(2):320-1. doi: 10.1016/j.jpeds.2009.11.060.

Authors

Gil Binenbaum¹, Christie J Bruno, Brian J Forbes, MaryAnn Snyder, Thomas J Mollen, Barbara Schmidt, Iyalla Peterside

Affiliation

¹ Division of Ophthalmology, Children's Hospital of Philadelphia and the University of Pennsylvania, 9-MAIN, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA. binenbaum@email.chop.edu

Abstract

A recent shortage of erythromycin ointment has resulted in the use of alternative agents for newborn ocular infection prophylaxis in the United States. We report a series of 26 newborns in whom a characteristic periocular ulcerative dermatitis developed after gentamicin ointment administration at 2 Philadelphia hospitals.

Publication types

Multicenter Study
Research Support, N.I.H., Extramural

MeSH terms

Administration, Topical
Anti-Bacterial Agents / adverse effects*
Antibiotic Prophylaxis / adverse effects*
Drug Eruptions / etiology
Eyelid Diseases / chemically induced*
Facial Dermatoses / chemically induced*
Female
Gentamicins / adverse effects*
Humans
Infant, Newborn
Male
Ointments
Philadelphia

Substances

Anti-Bacterial Agents
Gentamicins
Ointments

Abstract

Publication types

MeSH terms

Substances

Grants and funding