Abstract
Gabapentin is an antiepileptic drug approved for adjunctive therapy for partial seizures. We report a case of a patient who had thrombocytopenia with the dose of 2400 mg/day of gabapentin. The causal relationship between gabapentin and thrombocytopenia was revealed by dramatic increase in thrombocyte count following the cessation of the gabapentin treatment. To our knowledge, this is the first case report with a hematopoietic side effect of gabapentin.
MeSH terms
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Adult
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Amines / administration & dosage
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Amines / adverse effects*
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Anticonvulsants / administration & dosage
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Anticonvulsants / adverse effects*
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Cyclohexanecarboxylic Acids / administration & dosage
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Cyclohexanecarboxylic Acids / adverse effects*
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Dose-Response Relationship, Drug
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Drug Therapy, Combination
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Epilepsies, Partial / drug therapy*
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Gabapentin
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Humans
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Male
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Thrombocytopenia / chemically induced*
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gamma-Aminobutyric Acid / administration & dosage
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gamma-Aminobutyric Acid / adverse effects*
Substances
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Amines
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Anticonvulsants
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Cyclohexanecarboxylic Acids
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gamma-Aminobutyric Acid
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Gabapentin