The Section on Endocrinology and the Committee on Genetics of the American Academy of Pediatrics, in collaboration with experts from the fields of pediatric endocrinology and genetics, developed this policy statement as a means of providing up-to-date information for the practicing pediatrician about current practice and controversial issues in congenital adrenal hyperplasia (CAH), including the current status of prenatal diagnosis and treatment, the benefits and problem areas of neonatal screening programs, and the management of children with nonclassic CAH. The reference list is designed to allow physicians who wish more information to research the topic more thoroughly.