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Febrile infant (younger than 90 days of age): Definition of fever

Hannah F Smitherman, MD
Charles G Macias, MD, MPH
Section Editors
Stephen J Teach, MD, MPH
Morven S Edwards, MD
Deputy Editor
James F Wiley, II, MD, MPH


This topic will review the definition of fever in young infants 7 to 90 days of age.

The evaluation and management of febrile young infants 7 to 90 days of age and of neonates younger than seven days is discussed separately:

(See "Febrile infant (younger than 90 days of age): Outpatient evaluation".)

(See "Febrile infant (younger than 90 days of age): Management".)

(See "Clinical features, evaluation, and diagnosis of sepsis in term and late preterm infants" and "Management and outcome of sepsis in term and late preterm infants".)

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Literature review current through: Nov 2017. | This topic last updated: Jan 03, 2017.
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  1. Greenhow TL, Hung YY, Pantell RH. Management and Outcomes of Previously Healthy, Full-Term, Febrile Infants Ages 7 to 90 Days. Pediatrics 2016; 138.
  2. Maniaci V, Dauber A, Weiss S, et al. Procalcitonin in young febrile infants for the detection of serious bacterial infections. Pediatrics 2008; 122:701.
  3. Kadish HA, Loveridge B, Tobey J, et al. Applying outpatient protocols in febrile infants 1-28 days of age: can the threshold be lowered? Clin Pediatr (Phila) 2000; 39:81.
  4. Baker MD, Bell LM. Unpredictability of serious bacterial illness in febrile infants from birth to 1 month of age. Arch Pediatr Adolesc Med 1999; 153:508.
  5. Bachur RG, Harper MB. Predictive model for serious bacterial infections among infants younger than 3 months of age. Pediatrics 2001; 108:311.
  6. Hui C, Neto G, Tsertsvadze A, et al. Diagnosis and Management of Febrile Infants (0-3 months). Evidence Report/Technology Assessment No. 205 (Prepared by the University of Ottawa: Evidence-based Practice Center under Contract No. HHSA 290-2007-10059-I). AHRQ Publication No. 12-E004-EF. Rockville, MD: Agency for Healthcare Research and Quality. March 2012. Available at http://www.ahrq.gov/research/findings/evidence-based-reports/febrinftp.html (Accessed August 3, 2015)
  7. Callanan D. Detecting fever in young infants: reliability of perceived, pacifier, and temporal artery temperatures in infants younger than 3 months of age. Pediatr Emerg Care 2003; 19:240.
  8. Non-contact thermometers for detecting fever: A review of clinical effectiveness. Rapid Response Report: Summary with Critical Appraisal. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health. 2014 PMID: 25520984.
  9. Teran CG, Torrez-Llanos J, Teran-Miranda TE, et al. Clinical accuracy of a non-contact infrared skin thermometer in paediatric practice. Child Care Health Dev 2012; 38:471.
  10. Fortuna EL, Carney MM, Macy M, et al. Accuracy of non-contact infrared thermometry versus rectal thermometry in young children evaluated in the emergency department for fever. J Emerg Nurs 2010; 36:101.
  11. Bonadio WA, Hegenbarth M, Zachariason M. Correlating reported fever in young infants with subsequent temperature patterns and rate of serious bacterial infections. Pediatr Infect Dis J 1990; 9:158.
  12. Pantell RH, Newman TB, Bernzweig J, et al. Management and outcomes of care of fever in early infancy. JAMA 2004; 291:1203.
  13. Grover G, Berkowitz CD, Lewis RJ, et al. The effects of bundling on infant temperature. Pediatrics 1994; 94:669.