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Evaluation and management of infertility in women of advancing age

Mary E Sabatini, MD, PhD
Section Editor
Robert L Barbieri, MD
Deputy Editor
Kristen Eckler, MD, FACOG


In many countries, the mean maternal age at first birth is rising. However, fertility declines with advancing age. Thus, many women in more advanced age groups are presenting for fertility evaluation and treatment.

This topic will discuss the background, evaluation, and treatment of infertility in women of advancing reproductive age (ARA). While the phrase "advanced maternal age," or AMA, has traditionally been used to describe these women, we prefer the broader phrase "advancing reproductive age" because it applies to all aspects of reproductive biology and not just maternity. Related topics on infertility in women are presented separately.

(See "Overview of infertility".)

(See "Evaluation of female infertility".)

(See "Treatments for female infertility".)

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Literature review current through: Nov 2017. | This topic last updated: Nov 07, 2017.
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