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Medline ® Abstract for Reference 57

of 'ERCP for pancreatic disease in children'

Efficiency of pancreatic duct stenting therapy in children with chronic pancreatitis.
Oracz G, Pertkiewicz J, Kierkus J, Dadalski M, Socha J, Ryzko J
Gastrointest Endosc. 2014 Dec;80(6):1022-9. Epub 2014 May 20.
BACKGROUND: Chronic pancreatitis (CP) is a rare disease in childhood. Although ERCP is commonly performed in children, the effect of pancreatic duct stenting therapy in children with CP is unknown.
OBJECTIVE: To investigate the efficacy of pancreatic duct stenting in children with CP.
DESIGN: Retrospective analysis.
SETTING: National referral center.
PATIENTS: A total of 208 children with CP hospitalized between 1988 and 2012.
INTERVENTIONS: ERCP with pancreatic duct stenting.
MAIN OUTCOME MEASUREMENTS: Results of endoscopic therapy and number of pancreatitis episodes per year before and after treatment.
RESULTS: A total of 223 pancreatic duct stenting procedures were performed in 72 children. The median number of stent replacements was 3 (range 1-21). A statistically significant decrease in the number of pancreatitis episodes per year was observed: from 1.75 to 0.23 after endoscopic treatment (P <.05). Pancreatic duct stenting was performed more frequently in patients with hereditary pancreatitis (61.5%) and in children with CP and anatomic anomalies of the pancreatic duct (65%; P <.05).
LIMITATIONS: Retrospective analysis with the assessment of adverse events based on medical history.
CONCLUSION: Pancreatic duct stenting therapy is a safe and effective procedure in children with CP. This therapy should be recommended especially for children with hereditary pancreatitis and patients with anatomic anomalies of the pancreatic duct.
Department of Gastroenterology, Hepatology and Feeding Disorders, The Children's Memorial Health Institute, Warsaw, Poland.