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Medline ® Abstract for Reference 23

of 'Epidemiology, pathogenesis, and microbiology of intravascular catheter infections'

The place of early haemoperfusion with polymyxin B fibre column in the treatment of sepsis.
Ronco C
Crit Care. 2005;9(6):631. Epub 2005 Oct 18.
Direct haemoperfusion with polymyxin B-immobilized fibre (PMX-F) is a promising treatment for Gram-negative sepsis in critically ill patients. Indeed, it has been used routinely in Japan for a decade. Recent evidence presented in this journal suggests that PMX-F can have a positive impact on outcome in patients with sepsis, although other reports in the literature have presented confusing or even conflicting results. This commentary considers whether the available evidence allows us to establish an appropriate role for PMX-F treatment in sepsis and what further work is needed.
Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy. cronco@goldnet.it