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Medline ® Abstract for Reference 43

of 'Epidemiology, microbiology and pathogenesis of plague (Yersinia pestis infection)'

The Role of Early-Phase Transmission in the Spread of Yersinia pestis.
Eisen RJ, Dennis DT, Gage KL
J Med Entomol. 2015 Nov;52(6):1183-92. Epub 2015 Aug 19.
Early-phase transmission (EPT) of Yersinia pestis by unblocked fleas is a well-documented, replicable phenomenon with poorly defined mechanisms. We review evidence demonstrating EPT and current knowledge on its biological and biomechanical processes. We discuss the importance of EPT in the epizootic spread of Y. pestis and its role in the maintenance of plague bacteria in nature. We further address the role of EPT in the epidemiology of plague.
Bacterial Diseases Branch, Division of Vectorborne Diseases, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO. dyn2@cdc.gov.