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Medline ® Abstract for Reference 75

of 'Epidemiology, clinical manifestations, and treatment of cytomegalovirus infection in immunocompetent adults'

Cytomegalovirus pneumonia in immunocompetent host: case report and literature review.
Grilli E, Galati V, Bordi L, Taglietti F, Petrosillo N
J Clin Virol. 2012 Dec;55(4):356-9. Epub 2012 Sep 10.
CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented. In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.
Second Infectious Diseases Division, INMI L.Spallanzani, 00149 Rome, Italy. elisabetta75@gmail.com