- Katharine Esselen, MD, MBA
Katharine Esselen, MD, MBA
- Instructor of Medicine
- Harvard Medical School
- Robert L Barbieri, MD
Robert L Barbieri, MD
- Editor-in-Chief — Obstetrics, Gynecology and Women's Health
- Section Editor — General Gynecology and Female Reproductive Endocrinology
- Kate Macy Ladd Professor of Obstetrics, Gynecology and Reproductive Biology
- Harvard Medical School
Endosalpingiosis is the presence of ectopic, cystic glands outside the fallopian tube that are lined with fallopian tube-type ciliated epithelium . Endosalpingiosis may occur in pelvic organs, including ovaries, fallopian tube serosa, uterine serosa, myometrium, or pelvic peritoneum. It may also occur in the bladder or in a retroperitoneal or axillary lymph node .
Endosalpingiosis is not well-studied, and the clinical features remain uncertain. It has been reported to be associated with pelvic pain, infertility, pelvic mass, and/or urinary symptoms [3-6]. However, the diagnosis is made only after surgical biopsy. A key challenge regarding this condition is to differentiate it clinically from endometriosis.
Another notable feature of endosalpingiosis is its histologic relationship to pelvic serous neoplasms (eg, lesions of low malignant potential, low-grade pelvic serous carcinoma). However, the role of endosalpingiosis as a risk factor or as part of the pathogenesis of these conditions is unknown.
The pathology, diagnosis, and management of endosalpingiosis will be reviewed here. Topics regarding endometriosis are discussed separately. (See "Endometriosis: Pathogenesis, clinical features, and diagnosis" and "Endometriosis: Treatment of pelvic pain".)
The prevalence of endosalpingiosis is difficult to establish. There are few data regarding this condition. In addition, endosalpingiosis is diagnosed only through surgical biopsy, so it is unknown if there are asymptomatic cases. It appears that in approximately one-third of cases, patient have coexisting endosalpingiosis and endometriosis .To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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