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Endometrial sampling procedures

Giuseppe Del Priore, MD, MPH
Section Editor
Barbara Goff, MD
Deputy Editor
Sandy J Falk, MD, FACOG


Equipment and techniques for office-based endometrial sampling has generally replaced the need for diagnostic dilation and curettage performed in the hospital [1]. These techniques provide a minimally invasive option for diagnosis of endometrial cancer, hyperplasia, and other endometrial pathology.

Techniques for office procedures for endometrial sampling will be reviewed here. Dilation and curettage and an overview of the diagnostic approach to endometrial evaluation for neoplasia, including both noninvasive and invasive methods, are discussed separately. (See "Dilation and curettage" and "Evaluation of the endometrium for malignant or premalignant disease".)


Office sampling versus dilation and curettage — Endometrial sampling offers a number of advantages compared with dilation and curettage:

Operative setting is an outpatient clinic, rather than an operating room.

May be performed without anesthesia or with only local anesthesia.

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Literature review current through: Nov 2017. | This topic last updated: Jul 06, 2017.
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